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From: Doctor John
Subject: The Forlorn Hope wins a battle
Date: 13 Aug 2016 10:23:43
Message: <57af2d6f@news.povray.org>
... but the war's not over.

I am officially in remission :-D Yesterday, I met with probably the best
Stem Cell Transplant consultant in Britain* (every medical person I've
met sings his praises). After the usual verbal sparring (designed so
that he could measure my mental and emotional state) we got down to
business.

His opening statement was "You're in remission, so ...". I managed to
keep myself from bouncing off the ceiling - I knew that what he was
going to say next was important. My choices boiled down to:
	1. Carry on with the regime I'm currently on.
	2. Go for an Autologous Stem Cell Transplant
	3. Go for an Allogeneic SCT from a relation
	4. Go for an Unrelated Allogeneic SCT

The prognoses for each choice were:
	1. You will relapse and probably (80%) be dead within 2 years.
	2. As above but this time 5 years. No risk of GvHD**
	3. GvHD raises it's ugly head. 15% mortality***. But 10 years#
	4. Again as above but up to 20% mortality. However, who knows##

I've rejected 1 and 2 out of hand, but any input about 3 and 4?


* Dr Robert Marcus of King's College Hospital, London
** Graft versus Host Disease - a real killer
*** That is within 1 year from GvHD or associated infections
# Now we're heading for a cure.
## Not enough data, but it looks promising


John (now in possession of Sgt Harper's 7-barrel volley gun)
-- 
It's not about bravery.
It's about doing what I need to do to win


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From: Stephen
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 10:48:09
Message: <57af3329$1@news.povray.org>
On 8/13/2016 3:23 PM, Doctor John wrote:
> I've rejected 1 and 2 out of hand, but any input about 3 and 4?

Firstly, well done. :D
The drinks are on you. :)

For point #3. How evil were you to your siblings when you were young?


-- 

Regards
     Stephen


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From: Doctor John
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 10:58:51
Message: <57af35ab$1@news.povray.org>
On 13/08/16 15:48, Stephen wrote:
> On 8/13/2016 3:23 PM, Doctor John wrote:
>> I've rejected 1 and 2 out of hand, but any input about 3 and 4?
> 
> Firstly, well done. :D
> The drinks are on you. :)
> 

Oops! Seem to have forgotten my wallet :-)

> For point #3. How evil were you to your siblings when you were young?
> 

Me? Evil? No more than than the usual inter-sibling rivalry but with
serious battlefield weapons.

John
-- 
It's not about bravery.
It's about doing what I need to do to win


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From: Stephen
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 12:12:13
Message: <57af46dd$1@news.povray.org>
On 8/13/2016 3:58 PM, Doctor John wrote:
> On 13/08/16 15:48, Stephen wrote:
>> On 8/13/2016 3:23 PM, Doctor John wrote:
>>> I've rejected 1 and 2 out of hand, but any input about 3 and 4?
>>
>> Firstly, well done. :D
>> The drinks are on you. :)
>>
>
> Oops! Seem to have forgotten my wallet :-)
>

Again?

I'll lend you a bullseye at the usual rate. :)

>> For point #3. How evil were you to your siblings when you were young?
>>
>
> Me? Evil? No more than than the usual inter-sibling rivalry but with
> serious battlefield weapons.
>

Prey that their memories are no better/worse than yours. ;)


-- 

Regards
     Stephen


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From: Jim Holsenback
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 15:08:17
Message: <57af7021$1@news.povray.org>
On 8/13/2016 10:23 AM, Doctor John wrote:
> I've rejected 1 and 2 out of hand, but any input about 3 and 4?

well they say that attitude is most of it and i'd say you've qualified 
... as for what's up next i'm thinking on the same lines as Stephen (#3) 
... attitude and genetics sounds like a potent arsenal to me


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From: Stephen
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 15:21:34
Message: <57af733e$1@news.povray.org>
On 8/13/2016 8:08 PM, Jim Holsenback wrote:
> On 8/13/2016 10:23 AM, Doctor John wrote:
>> I've rejected 1 and 2 out of hand, but any input about 3 and 4?
>
> well they say that attitude is most of it and i'd say you've qualified
> .... as for what's up next i'm thinking on the same lines as Stephen
> (#3) .... attitude and genetics sounds like a potent arsenal to me
>

He certainly has an attitude. ;)

-- 

Regards
     Stephen


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From: clipka
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 17:44:44
Message: <57af94cc$1@news.povray.org>
Am 13.08.2016 um 16:23 schrieb Doctor John:

> I am officially in remission :-D

Congratulations about that!

> I've rejected 1 and 2 out of hand, but any input about 3 and 4?

Can't give any recommendation, except for the obvious: Choose the best
one ;)


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From: Jim Henderson
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 20:20:07
Message: <57afb937$1@news.povray.org>
On Sat, 13 Aug 2016 15:23:42 +0100, Doctor John wrote:

> ... but the war's not over.
> 
> I am officially in remission :-D Yesterday, I met with probably the best
> Stem Cell Transplant consultant in Britain* (every medical person I've
> met sings his praises). After the usual verbal sparring (designed so
> that he could measure my mental and emotional state) we got down to
> business.
> 
> His opening statement was "You're in remission, so ...". I managed to
> keep myself from bouncing off the ceiling - I knew that what he was
> going to say next was important. My choices boiled down to:
> 	1. Carry on with the regime I'm currently on.
> 	2. Go for an Autologous Stem Cell Transplant 3. Go for an 
Allogeneic
> 	SCT from a relation 4. Go for an Unrelated Allogeneic SCT
> 
> The prognoses for each choice were:
> 	1. You will relapse and probably (80%) be dead within 2 years. 2. 
As
> 	above but this time 5 years. No risk of GvHD**
> 	3. GvHD raises it's ugly head. 15% mortality***. But 10 years# 4. 
Again
> 	as above but up to 20% mortality. However, who knows##
> 
> I've rejected 1 and 2 out of hand, but any input about 3 and 4?
> 
> 
> * Dr Robert Marcus of King's College Hospital, London ** Graft versus
> Host Disease - a real killer *** That is within 1 year from GvHD or
> associated infections # Now we're heading for a cure.
> ## Not enough data, but it looks promising
> 
> 
> John (now in possession of Sgt Harper's 7-barrel volley gun)

That is *EXCELLENT* news!  Very pleased to hear this.

Jim



-- 
"I learned long ago, never to wrestle with a pig. You get dirty, and 
besides, the pig likes it." - George Bernard Shaw


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From: Jim Henderson
Subject: Re: The Forlorn Hope wins a battle
Date: 13 Aug 2016 20:24:47
Message: <57afba4f$1@news.povray.org>
On Sat, 13 Aug 2016 15:08:08 -0400, Jim Holsenback wrote:

> On 8/13/2016 10:23 AM, Doctor John wrote:
>> I've rejected 1 and 2 out of hand, but any input about 3 and 4?
> 
> well they say that attitude is most of it and i'd say you've qualified
> ... as for what's up next i'm thinking on the same lines as Stephen (#3)
> ... attitude and genetics sounds like a potent arsenal to me

In my entirely non-medical opinion, option 3 certainly *seems* like it's 
got the best potential.  But I know very little about medicine. :)

Jim



-- 
"I learned long ago, never to wrestle with a pig. You get dirty, and 
besides, the pig likes it." - George Bernard Shaw


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From: Thomas de Groot
Subject: Re: The Forlorn Hope wins a battle
Date: 14 Aug 2016 02:56:44
Message: <57b0162c$1@news.povray.org>
On 13-8-2016 16:23, Doctor John wrote:
> ... but the war's not over.

It never is; still, congratulations with this excellent state-of-the-art!

As said by others already, personally I would go for #3 and if 
unavailable for #4.

Stephen is right of course (when is he not?) ;-)


-- 
Thomas


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